Innovative approaches to treatment resistant depression

See Dr. Nasrallah’s June editioial in Current Psychiatry, June, 2012 p 4-5 on treating depression.  Also see Dr. Timothy R. Jennings’ comments regarding the ethical need to recommend TMS treatment before using atypical antipsychotics due to its efficacy and the lack of side effects in Current Psychiatry Vol. 11, No. 10 at

The Daily Buzz

This television program will air a 3+ minute demonstration of TMS Therapy with Dr. Randy Pardell and his patient Martha Rhodes on September 12th at 7:20 am.  To find this program on your local station go to

Magnetic Therapy Can Ease Depression, Doctors say

USA Today ran an article about TMS in their August 19, 2012 edition.  The link for the article is Ny1cTR.  Check it out!

Foods That Fight Depression from @everydayhealth by Chris lliades, MD

Are there depression fighting foods? A growing body of research says yes.
Recent studies hsve found evidence that foods such as cold-water fish (salmon, sardines,and tuna,for example), walnuts and canola oil may be especially beneficial in fighting depression, thanks to an abundance of omega-3 fatty acids. This may help to explain why Scandinavian and Asian countries, which boast fish-rich diets, also have lower rates of depression.
Researchers at McLean Hospital in Belmont,Mass.,have found that foods rich in uridine have positive effects on mood. Uridine is a natural substance found in sugar beets and molasses, which make these foods also good for treating depression.
Farther afield, Japanese researchers found that a diet high in fish protects people from depression and suicide, while in Finland a team of researchers surveyed 1,767 residents and concluded that eating fish more than twice a week has a protective effect against suicide and depression.
Exactly how these foods fight depression is not known. Researchers think that they may cause changes to some fats in brain membranes,making it easier for chemicals to pass through.The study at McLean hospital used laboratory rats, and researchers there caution that the metabolism of rats and humans is quite different.
Kathleen Franco, MD, professor of medicine and psychiatry at the Cleveland Clinic Lerner College of Medicine in Ohio, believes that diet and supplements, along with medication and psychotherapy, have a role in depression treatment. “It is recommended that individuals eat a healthy diet including fruits and vegetables with antioxidants; omega-3 fatty acids found in salmon, tuna and some other fish; and vitamins that include all the Bs,”says Dr. Franco.
Others are less convinced about the role of supplements and foods for depression. “Dietary supplements such as St. John’s wort and others have less consistent support in research studies and thus may not be effective for depression, says Richard Shadick, PhD, adjunct professor of psychology and director at the Pace University Counseling Center in New York City. “However, one way of controlling your diet that can improve your mood is limiting alcohol.”
Foods rich in omega-3 acids are not the only ones that have been studied for their effect on depression.Other foods or dietary supplements that may be beneficial include:

B vitamins. Studies suggest that if you have low levels of the B vitamin folic acid and high levels of a protein called homocysteine, you are more likely to be depressed. Folic acid, vitamin B2,B6,and B12 have all been shown to decrease levels of homocysteine. You can be sure to get enough B vitamins by eating a diet high in fruits, vegetables,nuts, whole grains and legumes.

Amino acids. Tryptophan is an important amino acis your body needs to make the brain chemical serotonin. Low levels of serotonin are believed to be a cause of depression. Several studies have shown that a diet high in tryptophan can improve depression. Tryptophan is found in foods high in protein, such as meat, fish, beans, and eggs.

Carbohydrates. All the carbohydrates you eat are broken down into sugar that your brain needs to function properly. However, eating too much sugar can cause peaks and valleys in your blood glucose levels that can cause or aggravate symptoms of depression. The best way to avoid these symptoms is to eat a diet low in refined carbohydrates and sugar and high in fruits and vegetables.

St. John’s wort. This plant has been used for centuries as a dietary supplement to treat depression and anxiety. Although some evidence has shown St. John’s wort effectiveness in treatin mild depression, two recent studies found that it was no more effective than a placebo for treating major depression.

Much of the evidence related to treating depression with food is not strong enough to say a particular food can cure depression, but active research continues. For now, most doctors agree that a depression diet, whether from food or dietary supplements, is not a substitute for proper medical care.

“Psychotherapy and medication are the most effective means of combating depression. It should be noted that for all forms of depression, it is important to see a mental health professional to determine the best treatment,” advises Dr. Shadick.

Dr Oz to Feature TMS

On Wednesday March 14th 2012 the Dr. Oz show featured TMS treatment for depression including an interview with a TMS patient. This was a great opportunity for more people to understand the benefits of this effective new treatment. The Dr. Oz show is on in the afternoon however you can click here for a list of links to content on his website regarding TMS.