Introducing One Day TMS (ONE-D)

Imagine treating your depression in a single day. What once required daily appointments over the course of 6-8 weeks can now be accomplished in just one visit. For the first time in the field of psychiatry, we have a protocol where depression can remit after a single day of treatment.

Now there’s One-D TMS—a breakthrough in interventional psychiatry that delivers a full course of transcranial magnetic stimulation (TMS) in one carefully structured day.

We are redefining what is possible in mental health care. As a leader in interventional psychiatry, we are proud to offer ONE-D (Optimized, Neuroplasticity-Enhanced Depression Treatment Regimen)—a revolutionary one-day TMS protocol for individuals suffering from treatment-resistant depression.

Developed from the latest neuroscience research and supported by promising clinical outcomes, ONE-D TMS provides rapid, durable relief—without the time commitment of days-to-weeks of TMS treatment.

Latest Development in Accelerated TMS: The ONE-D (Optimized Neuroplastogen-Enhanced Depression) regimen, designed to make TMS treatment faster, more affordable, and accessible.

Accelerated Full Course: ONE-D delivers a patient’s entire course of Transcranial Magnetic Stimulation (TMS) therapy—conventionally requiring weeks of visits—in a single day.

Intensive, Spaced Sessions: The single-day treatment involves 20 sessions of high-intensity, 3-minute intermittent Theta-Burst Stimulation (iTBS), the same pulse sequence used in Stanford’s SAINT protocol, with sessions repeated every 30 minutes to allow for brain recovery and maximal plasticity.

Neuroplastogen Enhancement: The protocol is “Neuroplastogen-Enhanced,” with a single pre-treatment dose of up to two supportive medications, to boost the brain’s ability to change (neuroplasticity) and improve the treatment’s effect: enhance learning and synaptic rewiring.